Histamine
A biogenic amine formed during the breakdown of proteins, plays a role in immune reactions and digestion.
Histamine is a biogenic amine that is formed by decarboxylation of the amino acid histidine. It has many functions in the body, including involvement in immune and allergic reactions, regulation of digestion and as a neurotransmitter. In histamine intolerance, there is an excessive accumulation of histamine in the body, which leads to various symptoms.
Related terms
Four types of sites in the body where histamine binds. Each type is located in different tissues and triggers different issues—explaining why histamine intolerance manifests with such a wide variety of symptoms.
An amino acid that is converted to histamine in the body. Its excess or poor processing can worsen HIT.
A group of chemical substances resulting from the decarboxylation of amino acids. Histamine is the best-known biogenic amine.
A biogenic amine similar to histamine that may exacerbate HIT symptoms in susceptible individuals.
A biogenic amine formed during the breakdown of proteins can worsen the symptoms of HIT.