Mast cells

General

Immune system cells that release histamine and other mediators in response to HIT triggers.

Mast cells are a key part of the immune system. In the context of histamine intolerance, they can be activated by various triggers such as food, allergens or stress. Once activated, they release large amounts of histamine and other inflammatory substances, which contribute to the symptoms of HIT.

Related terms

FermentationGeneral

The process by which microorganisms convert substances. It is key in HIT because it increases the histamine content of food.

Histamine intolerance (HIT)General

The inability of the body to properly break down histamine, which leads to its excessive accumulation and manifestations.

Histamine liberatorsGeneral

Substances that release histamine from cells, worsening the symptoms of HIT.

Cumulative effectGeneral

A build-up of histamine in the body from various sources that exceeds tolerance and triggers symptoms.

Swiss Interest Group Histamine Intolerance (SIGHI)General

An independent non-profit organization (Schweizerische Interessengemeinschaft Histamin-Intoleranz) that specializes in research, education and support for people suffering from histamine intolerance (HIT) and related disorders of mast cell metabolism.

More information

Mast cells | Glossary